What's the Buzz for March 2016

Dean Reece
Dean Reece

What’s on my mind this month is the importance of collaborative research, which is vital to advancing science and medicine aimed at improving human health and wellbeing.

The School of Medicine (SOM) has made a concerted effort to promote a culture of collaboration that transcends disciplines and departments, to bring our best investigators together to work toward solving the most complex medical problems today. We have devoted significant resources to foster these partnerships, and established a number of opportunities to increase team science across the SOM, University of Maryland, Baltimore (UMB) campus, and the University System of Maryland (USM). These initiatives include:

  • The Dean’s Challenge Award, with a goal of answering important questions underlying human health and disease by encouraging senior SOM scientists to catalyze the launch of major “Big Science” research programs within the school and across departments, centers, institutes and programs.
  • The School of Medicine Research Consortium Units (RCUs), such as the Brain Science RCU, interdisciplinary research groups that conduct large, multi-disciplinary, research studies by leveraging collaborations between senior physician-scientists, scientists, and other laboratory, translational, and clinical investigators throughout the SOM.
  • The Special Trans-Disciplinary Recruitment Award Program (STRAP) Initiative, with the goal of expanding the SOM research portfolio and funding base by encouraging multiple academic units to jointly recruit well-funded scientists and/or physician-scientists who have an excellent track record of publishing, teaching, and a history of mentoring students and/or trainees.
  • The University of Maryland Research and Innovation Seed Grant Program which supports new research foci, conducted by creative teams of USM investigators working across disciplinary boundaries and campuses, that could parlay into submission of innovative basic and translational science research proposals to federal, public or private funding agencies.

These programs, funded by start-up money that pales in comparison to million-dollar NIH grants, have made great achievements. Faculty conducting complementary research are now working together. Investigators who may never have crossed professional paths in the past are meeting regularly to talk about their science. Grant and patent applications have been submitted by new teams of researchers, and innovative approaches to medical problems are being explored. Companies have been formed, and our economic impact on the State has increased.

Most important to our goal of fostering inclusive research, we decided to take on the challenge of establishing a robust University of Maryland Clinical Translational Science Institute (UM CTSI). With partners from all the UMB schools, as well as the University of Maryland, College Park (UMCP), the overall objective of the UM CTSI is to rapidly transform basic discoveries and mechanistic understanding of pathophysiologic processes efficiently and safely into novel therapies and strategies to decrease morbidity and mortality, thereby dramatically impacting human health and wellbeing.

The UM CTSI has had some successes, such as the establishment of the University of Maryland Center for Health-Related Informatics and Bioimaging (CHIB) and the creation of the Research HARBOR (Helping Advance Research By Organizing Resources). However, we can—and should—do more to increase the collaboration between research programs across our campuses. We have some incredible colleagues doing amazing science and should capitalize upon this fact.

For example, the UM Center for Sports Medicine, Health & Human Performance, featured in this issue of the SOMnews, is a shining example of what can happen when UMCP and the SOM work together. The strength of our programs comes from the partnerships we have formed with our colleagues. Just as the UM School of Medicine is stronger for its collaboration with the UM Medical System, so, too, is our research portfolio buoyed by the breadth, depth and diversity of the faculty experts within our School, Campus and University System. I commend those who have already reached across disciplines to expand their research perspectives, and I strongly encourage you to seek out new members for your research teams who can bring a unique perspective to the scientific questions you are working to answer. Only by working cooperatively can we hope to achieve our ultimate goal of improving the health of all humankind.

In the relentless pursuit of excellence, I am

Sincerely yours,

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E. Albert Reece, MD, PhD, MBA
Vice President for Medical Affairs, University of Maryland
John Z. and Akiko K. Bowers Distinguished Professor and
Dean, University of Maryland School of Medicine

 


Kudos to our colleagues who are experts in their fields and give their all to represent the School of Medicine!

Bhutta_AdnanAdnan Bhutta, MBBS, FAAP, Associate Professor, Department of Pediatrics, was an invited speaker at the 14th Shaukat Khanum Cancer Symposium, an international conference held in Lahore, Pakistan, where he presented “Hemodynamic Management of Critically Ill Children with Malignancies.” He also gave Pediatric Grand Rounds on “Quality Improvement in Pediatrics” at the Children’s Hospital and The Institute of Child Health in Lahore.

Cross_Alan_200Alan Cross, MD, Professor of Medicine, Institute for Global Health, presented “Back to the Future: Anti-Endotoxin Vaccines for the Prevention and Treatment of Sepsis” at Vaccine R&D 2015 on November 3 in Baltimore. He also was an invited panelist for an FDA Public Workshop on “Non-Microbial Biomarkers of Infection for In Vitro Diagnostic Device Use” on October 16 at the FDA in Silver Spring, MD.

Robert EdelmanRobert Edelman, MD, Professor of Medicine, Institute for Global Health, presented Department of Medicine Grand Rounds on “Biological Terrorism: What Health Care Professionals Should Know” on October 22 at Sinai Hospital Medical Center in Baltimore.

Ben LawnerBenjamin Lawner, DO, MS, EMT-P, Assistant Professor, Department of Emergency Medicine, delivered the keynote address “Critical Care in the Air—and Everywhere!” at the 2015 Eastern Shore Emergency and Critical Care Symposium, held at Chesapeake College in Wye Mills, MD, on November 12. This annual conference is sponsored by Maryland ExpressCare, the regional communications and critical care transport system, and attended by critical care transport and hospital-based professionals from the University of Maryland Medical System network. Also on the faculty for this year’s event were Walter Atha, MD, Clinical Assistant Professor, Department of Emergency Medicine; Jenifer Fahey, CNM, MPH, Assistant Professor, Department of Obstetrics & Gynecology; Marcella Wozniak, MD, PhD, Associate Professor, Department of Neurology; Lewis Rubinson, MD, PhD, Associate Professor, Department of Medicine; Thomas Chiccone, MD, Clinical Assistant Professor, Department of Emergency Medicine; Dayanand Bagdure, MBBS, MPH, Assistant Professor, Department of Pediatrics; Colonel Raymond Fang, MD, Clinical Associate Professor, Department of Surgery, and Director, US Air Force Center for Sustainment of Trauma and Readiness Skills (C-STAR); and Lisa Booze, PharmD, Clinical Coordinator, Maryland Poison Center, University of Maryland School of Pharmacy.

David RaskoDavid Rasko, PhD, Associate Professor of Microbiology & Immunology, Institute for Genome Sciences, presented “Comparative Genomics and Transcriptomics” at the University of Pennsylvania Department of Microbiology on November 20. Dr. Rasko also presented “Comparative Genomics and Transcriptomics For the Study of Pathogenesis” at Uniformed Services University of the Health Sciences, Department of Microbiology & Immunology, on November 30.

Jacques RavelJacques Ravel, PhD, Professor of Microbiology & Immunology, and Associate Director, Genomics, Institute for Genome Sciences, participated in the CNRS-sponsored HPV/Microbiota workshop in Montpellier, France, on November 13, where he gave a keynote presentation on “Interactions Between the Vaginal Microbiota, the Host and Sexually Transmitted Infections.”

Paul WellingPaul Welling, MD, Professor, Department of Physiology, was the keynote lecturer at the 8th International Aldosterone Meeting in Zermatt, Switzerland in October, and was a featured lecturer at the American Society of Nephrology Annual Meeting in San Diego, CA, in November. His talks highlighted recent discoveries of his laboratory on the molecular bases of sodium and potassium balance, which are transforming our understanding of salt retention in hypertension.

A job well done to all who have kept us in the media spotlight!

Berman_BrianBrian Berman, MD, Professor of Family & Community Medicine and Director, Center for Integrative Medicine, was quoted extensively in the December issue of Baltimore Magazine in a section called “Another Way to Wellness.”

driscoll_colleenColleen Hughes Driscoll, MD, Assistant Professor, Department of Pediatrics, appeared on WBAL-TV 11 News on November 24, 2015, where she spoke about the treatment of newborns with opiate exposure.

Julie Dunning HotoppJulie Dunning Hotopp, PhD, Associate Professor of Microbiology & Immunology, Institute for Genome Sciences, was quoted in the December 7, 2015 Washington Post article “When Labs Clash Over Tardigrade DNA, That’s Just Science Working as It Should.”

Matthew LaurensMatthew Laurens, MD, MPH, Associate Professor of Pediatrics, Center for Vaccine Development, was quoted in the November 5, 2015 Washington Post story “Unsettling Finding From CDC Investigation: Tapeworms Can Transmit Cancer Cells to Humans.” Because of this, he was contacted by CNN and asked to write an opinion piece on “How Can a Tapeworm Cause Cancer?” that was published online on November 9.

Congratulations to the following who have received honors!

New UMB logoNeha Bhooshan, MD, PhD, and James Snider, III, MD, both Chief Residents in the Department of Radiation Oncology, received Scholar Awards from the Lurie Cancer Center to support travel and attendance at the Lynn Sage Breast Cancer Symposium/Scholars Program, held October 29 through November 1 in Chicago, IL.

czinnSteven Czinn, MD, Chair of the Department of Pediatrics, was named the Rouben and Violet Jiji Foundation Professor of Pediatrics on December 1.

Thomas HornyakThomas Hornyak, PhD, Associate Professor, and Bishal Tandukar, Graduate Student, both from the Department of Biochemistry & Molecular Biology, received a Prize of Excellence for the presentation “Quiescence and Proliferative Properties of Melanocyte Stem Cell Subpopulations in Bulge and Secondary Hair Germ Region of Hair Follicle” at the Annual Meeting of the Pan-American Society for Pigment Cell Research held in Orange, CA, from September 27–30, 2015.

We applaud our colleagues on their recent appointments!

New UMB logoJanine Good, MD, Associate Professor, Department of Neurology, has been appointed by the American Headache Society Board of Directors to lead a special Interest section on Electronic Medical Records (EMR). Goals and objectives of this section will be to: inventory what systems headache specialists are using, share tools for optimizing systems to fine-tune best practices, workflows, content, patient management/engagement, identify ways to improve end-user and patient satisfaction using the EMR, and, lastly, identify ways EMR data may be shared across systems, state, and nation.

Miriam LauferMiriam Laufer, MD, MPH, Associate Professor of Pediatrics, Institute for Global Health, was recently appointed as a Section Editor for the American Journal of Tropical Medicine and Hygiene.

Susan MendleySusan Mendley, MD, Associate Professor, Department of Pediatrics, has been appointed to a five-year term as Editor-in-Chief of Pediatric Research, the official journal of the societies of SPR (Society for Pediatric Research), APS (American Pediatrics Society), and the European SPR, effective January 1.

Congratulations to our very productive faculty on their recent grants and contracts!

Feigenberg_StevenSteve Feigenberg, MD, Professor, Department of Radiation Oncology, received a grant for up to $202,933 from Alliance Foundation Trials, LLC, as site PI for the clinical trial “ABT-888: A Phase 1 Dose Escalation and Phase 2 Randomized Placebo-Controlled Study of the Efficacy and Tolerability of Veliparib in Combination With Paclitaxel/Carboplatin-Based Chemoradiotherapy Followed by Veliparib and Paclitaxel/Carboplatin Consolidation in Subjects With Stage III Non–Small Cell Lung Cancer (NSCLC).”

New UMB logoBrian Johnson, Graduate Student, Department of Physical Therapy & Rehabilitation Science, has received a two-year, $3,000 Behavioral Research Grant from Qualtrics to support research to investigate how bimanual functional performance influences daily functional activities for individuals with stroke utilizing an online survey.

Minesh MehtaMinesh Mehta, MB, ChB, Professor, Department of Radiation Oncology, received a grant for up to $2,844 from Adelphi Values LLC, for participation in the clinical trial “Qualitative Caregiver and Patient Interviews: Understanding the Impact of Whole Brain Radiation Therapy on Patients With Non–Small Cell Lung Cancer With Brain Metastases.”

Elias MelhemElias Melhem, MD, PhD, Professor and the Dean John M. Dennis Chairman, Department of Diagnostic Radiology & Nuclear Medicine, received a $114,425 grant from GE for “Comparative Study of Conventional 1.5 and 3.0T MR Images With Synthetically Reconstructed MR Images.” The study involves evaluating a novel technique that has the potential for reducing the length of MRI exam times.

Hats off to those who have been published!

Clement AdebamowoClement Adebamowo, BM, ChB, ScD, Professor of Epidemiology & Public Health, Institute of Human Virology, was last author on “Influence of Spirituality and Modesty on Acceptance of Self-Sampling for Cervical Cancer Screening” in PLoS One, 2015 Nov 3;10(11):e0141679.

AntonicVlado Antonic, PhD, Faculty Research Associate, Department of Radiation Oncology, was among the co-authors on “Fire on Cruise Ships—An Underestimated Risk in Travel Medicine” in Travel Medicine and Infectious Disease, 2015 Nov-Dec;13(6):509-10.

Cynthia BearerCynthia Bearer, MD, PhD, the Mary Gray Cobey Professor of Neonatology, and Sandra Mooney, MD, Associate Professor, both from the Department of Pediatrics, were among the co-authors on “Choline Ameliorates Deficits in Balance Caused by Acute Developmental Ethanol Exposure” in Cerebellum, 2015 Aug;14(4):413-20. Drs. Bearer and Mooney, along with Alison Falck, MD, Assistant Professor; Shiv Kapoor, MD, Assistant Professor; and Dina El-Metwally, MB, BCh, PhD, Assistant Professor, all also from the Department of Pediatrics, were among the co-authors on “Developmental Exposure to Environmental Toxicants” in Pediatric Clinics of North America, 2015 Oct;62(5):1173-97. Dr. Bearer was also a co-author on “Expanding Research, Relevance and Reach” in Pediatric Research, 2016 Jan;79(1-1):2.

Maureen BlackMaureen Black, PhD, the John A. Scholl, MD, and Mary Louise Scholl, MD, Professor in Pediatrics, was among the co-authors on “Integrating Nutrition and Child Development Interventions: Scientific Basis, Evidence of Impact, and Implementation Considerations” in Advances in Nutrition, 2015 Nov;6(6):852-9.

Miriam LauferSara Boudová, MD/PhD Student; Titus Divala, MD, a Physician working with Dr. Miriam Laufer’s clinical trials in Malawi; Lauren Cohee, MD, Infectious Diseases Fellow in Pediatrics; and Miriam Laufer, MD, MPH, Associate Professor of Pediatrics, all from the Institute for Global Health, were among the co-authors on “The Prevalence of Malaria at First Antenatal Visit in Blantyre, Malawi Declined Following a Universal Bed Net Campaign” in Malaria Journal, 2015 Oct 29;14(1):422.

Delia ChiaramonteDelia Chiaramonte, MD, Assistant Professor of Family & Community Medicine, and Associate Director and Director of Education, Center for Integrative Medicine; Chris D’Adamo, PhD, Assistant Professor of Family & Community Medicine, and Director of Research, Center for Integrative Medicine; and Sania Amr, MD, Professor, Department of Epidemiology & Public Health, co-authored “Implementation of an Integrative Medicine Curriculum for Preventive Medicine Residents” in American Journal of Preventive Medicine, 2015 Nov;49(5 Suppl 3):S249-S256.

Creath_RobertRob Creath, PhD, Assistant Professor, and Mark Rogers, PT, PhD, FAFTA, Professor and Chair, both from the Department of Physical Therapy & Rehabilitation Science, were among the co-authors on “Variability of Anticipatory Postural Adjustments During Gait Initiation in Individuals With Parkinson Disease” in Journal of Neurophysiology, 2015 Dec 1 [Epub ahead of print].

Cross_Alan_200Alan Cross, MD, Professor of Medicine, Institute for Global Health, was among the co-authors on “Phase 1 Testing of Detoxified LPS/Group B Meningococcal Outer Membrane Protein Vaccine With and Without Synthetic CPG 7909 Adjuvant for the Prevention and Treatment of Sepsis” in Vaccine, 2015 Nov 27;33(48):6719-6726.

Barry DalyBarry Daly, MD, Professor, Department of Diagnostic Radiology & Nuclear Medicine, was among the co-authors on “Cross-Sectional Imaging of Thoracic and Abdominal Complications of Cerebrospinal Fluid Shunt Catheters” in Emergency Radiology, 2015 Nov 26 [Epub ahead of print]. He was also among the co-authors on “The First Use of Postmortem 3D Computed Tomography Images as Evidence in U.S. Criminal Courts: A Report of Four Cases” in Academic Forensic Pathology, 2015;5(3):650-661, and the invited review “The Current and Potential Future Role of Postmortem Computed Tomography in Medicolegal Death Investigation” in Academic Forensic Pathology, 2015;5(4):590-602.

Vasken DilsizanVasken Dilsizian, MD, Professor, Department of Diagnostic Radiology & Nuclear Medicine, was a co-author on the Editorial page “Molecular Imaging: From Deep Pearl Diving to Enlightenment” in Journal of the American College of Cardiology Cardiovascular Imaging, 2015 Dec;8(12):1472-1474.

Richard EckertRichard Eckert, PhD, the John F.B. Weaver Professor and Chair, Department of Biochemistry & Molecular Biology, and colleagues published multiple manuscripts describing identification of epidermal cancer stem cell survival proteins as prevention and therapy targets, including “Transglutaminase Is a Tumor Cell and Cancer Stem Cell Survival Factor” in Molecular Carcinogenesis, 2015 Oct; 54(10):947-958; “Type II Transglutaminase Stimulates Epidermal Cancer Stem Cell Epithelial-Mesenchymal Transition” in Oncotarget, 2015 August 21; 6(24): 20525–20539; “Survival Skin Cancer Stem Cells Requires the EzH2 Polycomb Group Protein” in Carcinogenesis, 2015 Jul;36(7):800-810; and “Transglutaminase Is Required for Epidermal Squamous Cell Carcinoma Stem Cell Survival” in Molecular Cancer Research, 2015 Jul;13(7):1083-94.

JEley_John_thumbohn Eley, PhD, Assistant Professor, Department of Radiation Oncology, was among the co-authors on “In Reply to Sahadevan” in International Journal of Radiation Oncology Biology Physics, 2015 Dec 1;93:1164–1165.

Samuel GalvagnoSamuel Galvagno, Jr, DO, PhD, MS, Associate Professor, Department of Anesthesiology; Robert Sikorski, MD, Assistant Professor, Department of Anesthesiology; Jon Mark Hirshon, MD, MPH, PhD, Professor, Department of Emergency Medicine; and Douglas Floccare, MD, MPH, Clinical Assistant Professor, Department of Emergency Medicine, co-authored “Helicopter Emergency Medical Services for Adults with Major Trauma” in the Cochrane Database of Systematic Reviews, 2015 Dec 15;12:CD009228.

Ann Gruber BaldiniAnn Gruber-Baldini, PhD, Professor; Denise Orwig, PhD, Associate Professor; and Jay Magaziner, PhD,
MS Hyg, Professor and Chair, all from the Department of Epidemiology & Public Health, were among the co-authors on “Rehabilitation Interventions for Older Individuals With Cognitive Impairment Post-Hip Fracture: A Systematic Review” in Journal of the American Medical Directors Association, 2015 Nov 20 [Epub ahead of print].

Haney MallematMichelle Hines, PharmD, Emergency Medicine Pharmacy Resident; Tareq Al-Salamah, MBBS, MPH, Administrative Fellow in Emergency Medicine; and Emily Heil, PharmD, Clinical Assistant Professor, School of Pharmacy, in collaboration with Haney Mallemat, MD, Assistant Professor; Michael Witting, MD, MS, Associate Professor; Michael Winters, MD, Associate Professor; and Bryan Hayes, PharmD, Clinical Assistant Professor, all from the Department of Emergency Medicine, and J. Kristie Johnson, PhD, Associate Professor, Department of Pathology, were among the co-authors on “Resistance Patterns of Escherichia coli in Women with Uncomplicated Urinary Tract Infection Do Not Correlate with Institutional Antibiogram” in Journal of Emergency Medicine, 2015 Dec, 49(6):998-1003. Based on culture results from otherwise healthy women with uncomplicated urinary tract infections treated in UMMC’s emergency department, the authors suspect that hospital antibiograms overestimate E. coli resistance rates for several antibiotics.

Jia_XiaofengXiaofeng Jia, BM, PhD, Associate Professor, Departments of Neurosurgery and Orthopaedics, was the senior author on “Information-Theoretical Quantifier of Brain Rhythm Based on Data-Driven Multiscale Representation” in Biomedical Research International, 2015 Nov 12 [Epub ahead of print].

Katja LangenKatja Langen, PhD, Associate Professor, Department of Radiation Oncology, was among the co-authors on “Physics: The Use of Magnetic Resonance Imaging For Radiation Therapy is Accelerating in Utility and Novelty” in International Journal of Radiation Oncology Biology Physics, 2015 Dec 1;93(5):953-956.

Richard LichensteinRichard Lichenstein, MD, Professor of Pediatrics, was lead author on “Television-Related Head Injuries in Children: A Secondary Analysis of a Large Cohort Study of Head-Injured Children in the Pediatric Emergency Care Applied Research Network” in Pediatric Emergency Care, 2015 Nov 6 [Epub ahead of print].

Erik LillehojErik Lillehoj, PhD, Associate Professor, Department of Pediatrics, co-authored the article “Dietary Capsicum and Curcuma longa Oleoresins Increase Intestinal Microbiome and Necrotic Enteritis in Three Commercial Broiler Breeds” in Research in Veterinary Science, 2015 Oct;102:150-158.

Mu-Han LinJolinta Lin, MD, Resident; Mu-Han Lin, PhD, Assistant Professor; Andrea Hall, Senior Dosimetrist; Bin Zhang, Associate Chief Dosimetrist; and William Regine, MD, the Isadore & Fannie Schneider Foxman Chair and Professor, all from the Department of Radiation Oncology, were among the co-authors on “Comparison of Bolus Electron Conformal Therapy Plans to Traditional Electron and Proton Therapy to Treat Melanoma in the Medial Canthus” in Practical Radiation Oncology, 2015 Nov 11 [Epub ahead of print].

Martinez_JosephJoseph Martinez, MD, Associate Professor, and Adam Geroff, MD, Assistant Professor, both from the Department of Emergency Medicine, published a clinical image and patient vignette about Sister Mary Joseph’s nodule in the Visual Diagnosis column of The Journal of Emergency Medicine, 2016 Jan;50:123-124.

Susan MendleySusan Mendley, MD, Associate Professor, Department of Pediatrics, was among the co-authors on “Duration of Chronic Kidney Disease Reduces Attention and Executive Function in Pediatric Patients” in Kidney International, 2015;87(4):800-6.

PranshuMohindraPranshu Mohindra, MD, Assistant Professor, Department of Radiation Oncology, was among the co-authors on “Simulation Study of High-Dose-Rate Brachytherapy for Early Glottic Cancer” in Brachytherapy, 2016 Jan-Feb;15(1):94-101.

Daniel MorganDaniel Morgan, MD, Associate Professor, Department of Epidemiology & Public Health, was first author on “Update on Medical Practices That Should Be Questioned in 2015” in JAMA Internal Medicine, 2015 Dec 1;175(12):1960-1964. Dr. Morgan was also a co-author with Max Masnick, Doctoral Candidate, Program in Epidemiology and Human Genetics; John Sorkin, MD, PhD, Professor, Department of Medicine; and Jessica Brown, PhD, Assistant Professor, and Anthony Harris, MD, MPH, Professor, both from the Department of Epidemiology & Public Health, on “Lack of Patient Understanding of Hospital-Acquired Infection Data Published on the Centers for Medicare and Medicaid Services Hospital Compare Website” in Infection Control and Hospital Epidemiology, 2016 Feb;37(2):182-187.

Smith_GordonGiora Netzer, MD, Associate Professor, Department of Medicine; Sarah Murthi, MD, Clinical Associate Professor, Department of Surgery; and Gordon Smith, MB, ChB, MPH, Professor, Department of Epidemiology & Public Health, were among the co-authors on “Injured Patients With Very High Blood Alcohol Concentrations” in Injury, 2016 Jan;47(1):83-88.

Michelle PearceMichelle Pearce, PhD, Assistant Professor of Family & Community Medicine, Center for Integrative Medicine, was among the co-authors on “Effects of Religious Versus Standard Cognitive Behavioral Therapy on Optimism in Persons with Major Depression and Chronic Mental Illness” in Depression and Anxiety, 2015 Nov;32(11):835-42. She was also among the co-authors on “Religious Coping Among Adults Caring for Family Members with Serious Mental Illness” in Community Mental Health Journal, 2016 Feb;52(2):194-202.

Cross_Alan_200Girish Ramachandran, PhD, Research Associate, and Alan Cross, MD, Professor of Medicine, both from the Institute for Global Health, were among the co-authors on “Potential Role of Autophagy in the Bactericidal Activity of Human PMNs for Bacillus anthracis” in Pathogens and Disease, 2015 Dec;73(9):ftv080.

Sabnis_GauriGauri Sabnis, PhD, Research Associate, and Angela Brodie, PhD, Professor, both from the Department of Pharmacology; Todd Gould, MD, Associate Professor, Department of Psychiatry; and Istvan Merchenthaler, MD, PhD, Professor, Department of Epidemiology & Public Health, were among the co-authors on “The Bioprecursor Prodrug 10b,17b-dihydroxyestra-1,4-dien-3-one Delivers 17b-estradiol Selectively to the Female Brain” in Science Translational Medicine, 2015;7(297):297ra113.

Soronson_BryanBryan Soronson, MPA, FACMPE, CRA, Administrator, Department of Neurology, was a co-author on the three-article series “How Neurologists Are Paid” in Neurology Clinical Practice, 2015 Sep 17 [Epub ahead of print].

SundararajanSripriya Sundararajan, MD, Assistant Professor; Cynthia Bearer, MD, PhD, the Mary Gray Cobey Professor of Neonatology; and Dina El Metwally, MD, Assistant Professor, all from the Department of Pediatrics, were among the co-authors on “Toxic Metal Contamination of Banked Blood Designated for Neonatal Transfusion” in Journal of Clinical Toxicology, 2015 Sep 31 [Epub ahead of print]. Drs. Sundararajan and Bearer were also among the co-authors on “Neonatal Gabapentin Withdrawal Syndrome” in Pediatric Neurology, 2015 Nov;53(5):445-7, and they co-authored a book chapter on “Role of Environmental Epigenetics in Perinatal and Neonatal Development” in Epigenetics, the Environment, and Children’s Health Across Lifespans, published by Springer in November 2015.

Charles WhiteCharles White, MD, Professor, Department of Diagnostic Radiology & Nuclear Medicine, was among the co-authors on “A Case of Complete Unroofed Coronary Sinus Syndrome Combined With Coronary Sinus Stenosis Leading to Asymptomatic Presentation” in Iranian Journal of Radiology, 2015 Jul 22;12(3):e16063.

Michael WittingMichael Witting, MD, MS, Associate Professor, Department of Emergency Medicine, and Getachew Teshome, MD, MPH, Assistant Professor, Department of Pediatrics, were among the co-authors on “Emergency Diagnostic Testing for Pediatric Nonfebrile Seizures” in American Journal of Emergency Medicine, 2015 Sep;33:1261-1264. Their co-authors were Ashley Strobel, MD, and Vikramjit Gill, MD, who were residents in UMMC’s combined emergency medicine/pediatrics program at the time of the study.

Ben LawnerA number of faculty and medical center staff contributed chapters to the second edition of Ciottone’s Disaster Medicine, which was published by Elsevier in November. This book is considered an authoritative text regarding the preparation for, assessment of, and response to natural and man-made disasters. Among the 200 chapter contributors from around the world were Department of Emergency Medicine faculty members Fermin Barrueto, MD, Clinical Associate Professor; Benjamin Lawner, DO, MS, EMT-P, Assistant Professor; Debra Lee, MD, Assistant Professor; Kinjal Sethuraman, MD, MPH, Assistant Professor; Jerrilyn Jones, MD, Assistant Professor; and David Freeman, MS, NRP, Clinical Instructor. Contributors from the University of Maryland Medical Center were Elizabeth Kencz, MD, Emergency Medicine Resident (at the time of manuscript preparation); Alexander Skog, BA, Emergency Medicine Research Assistant; James Chang, BS, MS, Director of Safety and Environmental Health; Diana Clapp, RN, CCRN, BSN, NRP, Quality Improvement Coordinator and EMS Liaison, Shock Trauma Center; and Nicole Mullendore, MSN, CRNP, Nurse Practitioner, Adult Emergency Department.

Winters_MichaelThe February issue of Emergency Medicine Clinics of North America contained articles written by two Department of Emergency Medicine faculty members. Michael Winters, MD, Associate Professor, and Michael Allison, MD, a 2015 graduate of the University of Maryland’s six-year emergency medicine/internal medicine/critical care medicine residency, contributed the article “Noninvasive Ventilation for the Emergency Physician” (34:51–62), and Haney Mallemat, MD, Assistant Professor, co-authored the article “Emergency Department Treatment of the Mechanically Ventilated Patient” (34:63–75). Amal Mattu, MD, Professor, Department of Emergency Medicine, and Consulting Editor for the Clinics series, wrote the foreword to this issue, the topic of which was respiratory emergencies.

Thomas MacvittieThe November 2015 issue of Health Physics was a special issue authored entirely by Thomas MacVittie, PhD, Professor, Department of Radiation Oncology, and his research group.

The topics and authors/co-authors from the Department were:

 

  1. Thomas MacVittie, PhD, Professor; Ann Farese, MA, MS, Assistant Professor; Kory Barrow, Research Specialist; Kaitlyn Kieta, Research Specialist; Cheryl Taylor-Howell, Research Specialist; Sean Kearney, Research Specialist, Cassandra Smith, Lab Supervisor; and Allison Gibbs, Lab Supervisor: “A MALDI-MSI Approach to the Characterization of Radiation-Induced Lung Injury and Medical Countermeasure Development” (2015;109:466–478).
  2. Thomas MacVittie, PhD, Professor; Pranshu Mohindra, MD, Assistant Professor; Kory Barrow, Research Specialist; Bradley Ruehle, Research Assistant; Jordan Parker, Research Assistant; Elisa Swartz, Research Specialist; Cheryl Taylor-Howell, Research Specialist; Kaitlyn Kieta, Research Specialist; Travis Dobbin, Research Assistant; and Adam Baron, Research Assistant: “The Evolving MCART Multimodal Imaging Core: Establishing a Protocol for Computed Tomography and Echocardiography in the Rhesus Macaque to Perform Longitudinal Analysis of Radiation-Induced Organ Injury” (2015;109:479–492).
  3. Ann Farese, MA, MS, Assistant Professor; Kim Hankey, PhD, Research Associate; and Thomas MacVittie, PhD, Professor: “Lymphoid and Myeloid Recovery in Rhesus Macaques Following Total Body X-Irradiation” (2015;109:414–426).
  4. Ann Farese, MA, MS, Assistant Professor; Thomas MacVittie, PhD, Professor; and Alex Bennett, Research Lead Specialist: “Comparing the Hematopoetic Syndrome Time Course in the NHP Animal Model to Radiation Accident Cases From the Database Search” (2015;109:493–501).
  5. Kim Hankey, PhD, Research Associate; Ann Farese, MA, MS, Assistant Professor; Thomas MacVittie, PhD, Professor, and Alex Bennett, Research Lead Specialist: “Citrulline as a Biomarker in the Non-Human Primate Total- and Partial-Body Irradiation Models: Correlation of Circulating Citrulline to Acute and Prolonged Gastrointestinal Injury” (2015;109:440–451).
  6. Ann Farese, MA, MS, Assistant Professor, and Thomas MacVittie, PhD, Professor: “Citrulline as a Biomarker in the Murine Total-Body Irradiation Model: Correlation of Circulating and Tissue Citrulline to Small Intestine Epithelial Histopathology” (2015;109:452–465).
  7. Thomas MacVittie, PhD, Professor; Ann Farese, MA, MS, Assistant Professor; Karl Prado, PhD, Professor; Alex Bennett, Research Lead Specialist; Cheryl Taylor-Howell, Research Specialist; Cassandra Smith, Lab Supervisor; and Allison Gibbs, Lab Supervisor: “The Effect of Radiation Dose and Variation in Neupogen® Initiation Schedule on the Mitigation of Myelosuppression During the Concomitant GI-ARS and H-ARS in a Nonhuman Primate Model of High-Dose Exposure With Marrow Sparing” (2015;109:427–439).
  8. Thomas MacVittie, PhD, Professor, and Ann Farese, MA, MS, Assistant Professor: “The Hematopoietic Syndrome of the Acute Radiation Syndrome in Rhesus Macaques: A Systematic Review of the Lethal Dose Response Relationship” (2015;109:342–366).
  9. Thomas MacVittie, PhD, Professor: “The MCART Consortium Animal Model Series: MCART Animal Model Refinement and MCM Development: Defining Organ Dose, Organ-Specific Tissue Imaging, Model Validation and the Natural History Between the Acute Radiation Syndrome (ARS) and the Delayed Effects of Acute Radiation Exposure (DEARE)” (2015;109:335–341).
  10. Thomas MacVittie, PhD, Professor: “The H-ARS Dose Response Relationship (DRR): Validation and Variables” (2015;109:391–398).
  11. Thomas MacVittie, PhD, Professor; Karl Prado, PhD, Professor; and Alex Bennet, Research Lead Specialist: “Mean Organ Doses Resulting From Non-Human Primate Whole Thorax Lung Irradiation Prescribed to Mid-Line Tissue” (2015;109:367–373).
  12. Ann Farese, MA, MS, Assistant Professor, and Thomas MacVittie, PhD, Professor: “An Interlaboratory Validation of the Radiation Dose Response Relationship (DRR) for H-ARS in the Rhesus Macaque” (2015;109:502–510).
  13. Thomas MacVittie, PhD, Professor: “Delayed Effects of Acute Radiation Exposure in a Murine Model of the H-ARS: Multiple-Organ Injury Consequent to
  14. Pei Zhang, PhD, Postdoctoral Fellow; Wanchang Cui, PhD, Research Associate; Kim Hankey, PhD, Research Associate; and Thomas MacVittie, PhD, Professor; Allison Gibbs, Lab Supervisor; Cassandra Smith, Lab Supervisor; Cheryl Taylor-Howell, Research Specialist; and Sean Kearney, Research Specialist: “Increased Expression of Connective Tissue Growth Factor (CTGF) in Multiple Organs After Exposure of Non-Human Primates (NHP) to Lethal Doses of Radiation” (2015;109:374–390).

 

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